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Scleroderma, fasciitis, and Eosinophilia Associated with the Ingestion of Tryptophan
NEJM 322:874-881, 9261990., Silver,R.M.,et al, 1990
See this aricle in Pubmed

Article Abstract
This illness resembles eosinophilic fasciitis and probably represents one aspect of the recently reported eosinophilia-myalgia syndrome.The development of the syndrome may result from a confluence of several factors,including the ingestion of tryptophan,exposure to agents that activate indoleamine-2,3-dioxygenase,and possibly,impaired function of the hypothalamic-pituitary-adrenal axis.
 
Related Tags
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eosinophilia
eosinophilia-myalgia syndrome
eosinophilic fasciitis
L-tryptophan
muscle cramp
muscle pain
paresthesias
pruritus
scleroderma
skin,lesions in neurologic disorders
skin,thickened

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